Prions are protein aggregates that can be transmitted between cells and are associated with human diseases including Creutzfeldt-Jakob disease, and in neurodegeneration as observed in ALS. Despite the important role of prion-like domains in human diseases, much about them remains a mystery. An international team of researchers, including Rohit Pappu, the Edwin H. Murty Professor […]
A Washington University in St. Louis team of engineers led by Jan Bieschke, assistant professor of biomedical engineering, and their German collaborators are studying how a compound found in green tea could have lifesaving potential for patients with multiple myeloma and amyloidosis, who face often-fatal medical complications associated with bone-marrow disorders. These patients are susceptible […]